LL-37
A human antimicrobial peptide studied in immune-defense and wound research.
Get told when a price moves or a lab test changes.
Observed median price
$78
Every observation
| Date | Observed |
|---|---|
| $64.95 | |
| $104.37 | |
| $45.00 | |
| $58.50 | |
| $63.00 | |
| $63.00 | |
| $63.00 | |
| $63.98 | |
| $64.95 | |
| $71.99 | |
| $71.99 | |
| $71.99 | |
| $71.99 | |
| $71.99 | |
| $71.99 | |
| $71.99 | |
| $71.99 | |
| $71.99 | |
| $71.99 | |
| $71.99 | |
| $71.99 | |
| $71.99 | |
| $71.99 | |
| $75.00 | |
| $75.00 | |
| $75.00 | |
| $75.00 | |
| $71.99 | |
| $71.99 | |
| $71.99 | |
| $71.99 | |
| $71.99 | |
| $71.99 | |
| $82.00 | |
| $75.00 | |
| $78.00 | |
| $78.00 | |
| $78.00 |
Median of 8 listings' 30-day changes; 9 excluded for insufficient history.
17
Active listings
1 · 99.3%
Independent lab tests
$45–$720
Observed price range
3
Known aliases
Read from the certificate, not re-measured by VialGrade. Purity is not a grade. Purity vs grade
Understand this compound
What is LL-37?
Preclinical / animal onlya.k.a. Cathelicidin, hCAP-18 (precursor form)Your body's own built-in antibiotic — a molecule the immune system uses to punch holes in microbes and rally immune cells. Studied for infections and wound healing.
Good to know: Native LL-37 is cytotoxic and hemolytic at higher concentrations and degrades rapidly in vivo, which is why most therapeutic development uses modified analogs rather than the native peptide.
How does LL-37 work?
The science
The only human cathelicidin antimicrobial peptide; it disrupts microbial membranes directly and also signals through the formyl peptide receptor FPRL-1/FPR2 to recruit and activate immune cells.
Mechanism of action from published research — how the molecule behaves, not a claim about any product or any human-use effect.
What is LL-37 researched for?
Studied for broad-spectrum antimicrobial, antiviral, wound-healing, and immunomodulatory applications.
- Immune & thymicStudied in immune-modulation and thymic-function research.
- Recovery & healingStudied in tissue-repair research — tendon, ligament, muscle, and wound-healing models.
How far has the research gone?
Preclinical / animal research — extensively studied in vitro and in animal wound/infection models, but poor stability and toxicity have kept it from clinical translation.
Where the science stands — an approved drug is not the same as the research-grade material a vendor sells, which is unregulated regardless.
What should I check before buying?
- Independent purity. Look for a third-party COA (Janoshik or MZ) showing a measured purity — not just a number the vendor typed.
- Batch match. The strongest evidence is a certificate for the exact batch you’ll receive, attributed to this vendor — check the cross-verification on the listing.
- Vendor reputation. See how the vendor is talked about in the community before trusting a new name.
Research context only — VialGrade never gives dosing, medical, or human-use guidance.
Current market
The LL-37 market
Every LL-37 listing we track — 17 in all. The standout picks first where the evidence supports them, then the full table, ranked by what a milligram really costs wherever the vendor published a strength we can read.
Open full marketLL-37 (10MG)
Ascension Peptides
$78$7.80/mg-51% vs median
Lowest price per mg that isn't flagged as suspiciously cheap.
UnavailableChecked 9 hours ago
LL-37 10MG
Simple PeptideC+
$54$5.40/mg-66% vs median
Lowest real cost per active mg — price divided by measured purity.
In stockChecked 2 days ago
LL-37 10MG 10MG
EZ PeptidesA
$78$7.80/mg-51% vs median
Ranked #3 of 13 listings by price per milligram.
In stockChecked 11 hours ago
LL-37 – 5mg
Ion PeptideC
$45$9.00/mg-43% vs median
Ranked #4 of 13 listings by price per milligram.
UnavailableChecked 14 days ago
LL-37 5MG 5MG
Modern AminosB
$47$9.40/mg-41% vs median
Ranked #5 of 13 listings by price per milligram.
In stockChecked 11 hours ago
Compare by real cost
Every LL-37 listing, cheapest per mg first
Sticker prices hide the size, so listings are ranked by what a milligram actually costs — with independently tested purity where it exists. All 17 are here: the last 4 are listings whose vendor never published a strength we can read, so they have no per-mg figure to sort on.
| # | Vendor | Size | Price | Per mg | Tested purity | Real $/active mg | |
|---|---|---|---|---|---|---|---|
| 1 | Simple Peptide | 10mg total | $54 | $5.40/mg · too cheap? | — | $5.44/mgbest value | View |
| 2 | Ascension PeptidesUnavailable | 10mg total | $78 | $7.80/mg | — | $7.85/mg | View |
| 3 | Ez Peptides | 10mg total | $78 | $7.80/mg | — | $7.85/mg | View |
| 4 | Ion PeptideUnavailable | 5mg total | $45 | $9.00/mg | — | $9.06/mg | View |
| 5 | Modern Aminos | 5mg total | $47 | $9.40/mg | — | $9.46/mg | View |
| 6 | Chameleon Peptides | 50mg total10-vial kit each | $490 | $9.80/mg | — | $9.87/mg | View |
| 7 | Swiss Chems | 5mg total | $72 | $14.4/mg | — | $14.5/mg | View |
| 8 | Swiss ChemsUnavailable | 50mg totalLL-37 (CAP-18) 5mg: KIT (10 vials) each | $720 | $14.4/mg | — | $14.5/mg | View |
| 9 | Biotech Peptides | 5mg total | $86 | $17.2/mg | — | $17.3/mg | View |
| 10 | Core Peptides | 5mg total | $89 | $17.8/mg | — | $17.9/mg | View |
| 11 | Umbrella Labs | 5mg total5 Milligrams each | $90 | $18.0/mg | — | $18.1/mg | View |
| 12 | Umbrella Labs | 2mg total | $45 | $22.5/mg | — | $22.7/mg | View |
| 13 | Chameleon Peptides | 5mg total | $298 | $59.5/mg | — | $59.9/mg | View |
| Listed, but not rankable — no published strength to price per mg | |||||||
| — | Simple Peptide | 1 vial | $45 | no size published | — | — | View |
| — | Nootropic Source | 1 vial | $65 | no size published | — | — | View |
| — | Purerawz | 1 vial | $104 | no size published | — | — | View |
| — | Behemoth LabzUnavailable | 1 vial | $109 | no size published | — | — | View |
Real $/active mg divides the price-per-mg by the measured purity — the honest cost of the actual peptide, so a 90%-pure vial isn’t compared as if it were 99%. Too cheap? flags a listing far below the market rate — often underdosing or a fake, not a deal. The crown marks the cheapest non-outlier; best value marks the lowest real cost per active mg. A vendor shown as Unavailable or Low stock is priced here but not currently buyable.
Independent testing
LL-37 — independent lab tests
Real, publicly verifiable third-party tests. Purity is read from the certificate itself. A test reflects one lab’s result for one submitted batch — not a guarantee that every vial matches.
How does this data get here?
Every record below is a real certificate of analysis, gathered two ways: from the public verification feeds that independent labs (like Janoshik) publish, and from the certificates vendors post on their own product pages. We open each certificate document and read the measured purity, content, batch, and date directly off it — a scraper can’t read a number printed inside an image, so this is done by machine vision, then recorded here with a link back to the original.
Nothing here is typed in by a vendor or invented by us. Where a certificate is missing, we say so rather than filling the gap.
We re-check the lab feed, too. A “still listed” tag means the certificate is currently public in Janoshik’s database — we re-verify against the live feed and stamp the date. If a cert is later pulled, the tag flips. It’s a freshness check on the same source, not a second independent opinion.
What a certificate does & doesn’t prove
Three different questions. Purity (“how clean?”), identity (“is it the right molecule?”, a mass-spec test), and content (“did I get the labeled mg?”) are separate. A vial can be 99% pure and still be the wrong peptide, or the right peptide underdosed. We flag the measured dose against the label above; underdosing is the most common real fraud.
Who submitted the sample matters. Most of these are vendor-submitted — the seller chose which vial to send, so one good certificate doesn’t prove every batch is the same. The gold standard is a blind test, where a buyer sends a vial they bought as a normal customer. Same label doesn’t prove same product; same batch number doesn’t prove same batch.
99.3%
highest tested purity
| Certificate | Manufacturer | Batch | Purity | Content / dose | Lab | |
|---|---|---|---|---|---|---|
| PeptideGurus | 3rd June 2026 | 99.32% | 7.83/7mg · full | Janoshik Analytical Still listed | Verify |
Tested batches
Batch test records for LL-37
The full test history for one batch — who picked the sample, who tested it, and what came back. It describes the vials that were tested, never every vial they sold.
What the research says
Scientific evidence & regulatory status
What the published literature actually shows about LL-37 — separate from any vendor’s marketing. Each finding links to its paper. This is education, not medical or dosing advice.
Regulatory status
No FDA-approved drug
An endogenous human cathelicidin peptide; synthetic LL-37 is not FDA-approved and remains investigational. FDA placed cathelicidin LL-37 in category 2 (significant safety risks) for compounding, citing immunogenicity risk by some routes and peptide-related impurities; the nomination was later withdrawn.
Honest overall read
LL-37 is a natural human innate-immunity peptide whose early human data are limited to a small Phase 1 melanoma trial; it showed dermatologic toxicity and has paradoxical cancer-promoting effects in some tissues, so it is far from a validated therapeutic.
A Phase 1 trial delivered weekly intratumoral LL-37 injections to melanoma patients; a case report from that trial documented a severe but reversible skin reaction (keratoacanthoma-like squamous proliferation and lichenoid dermatitis) that resolved within two months of stopping therapy.
Documented dermatologic toxicity in a trial participant; overall efficacy results remain largely unpublished.
read the sourceA review summarizes evidence that LL-37 has context-dependent, sometimes opposite roles in cancer, promoting tumor growth and invasion in some cancers while being suppressive in others.
LL-37 can be pro-tumorigenic depending on tissue, a genuine concern that undercuts blanket 'immune-boosting' or 'anti-cancer' marketing claims.
read the sourceResearch-use-only — not FDA-approved
Sold “for research use only,” this compound is not FDA-approved for human use and has not been evaluated for safety, purity, or sterility in people. It is generally not a scheduled controlled substance, so buying it as a research chemical is typically not itself a drug crime — but marketing or using it as a drug is not lawful, and it is not a dietary supplement.
General information, not legal or medical advice. VialGrade sells nothing and encourages no human use.
Research notes aren’t product proof
Research summaries describe published literature and market data only. They do not establish the identity, quality, safety, or legal status of any listed physical product.