Live data — every record is aggregated from real public sources. VialGrade never sells; it links out to the vendor.
VialGrade
All compounds
GLP-1 / metabolic
Live data

Mazdutide

Weight & metabolic

A GLP-1/glucagon dual agonist studied in weight and metabolic research.

IBI362LY3305677

Get told when a price moves or a lab test changes.

Observed median price

$120

Δ —
Every observation
DateObserved
$79.00
$162.47
$119.99
$159.99
$159.99
$119.99
$162.47
$162.47
$162.47
$162.47
$159.99
$162.47
$162.47
$159.99
$162.47
$162.47
$162.47
$162.47
$159.99
$162.47
$162.47
$162.47
$159.99
$162.47
$162.47
$159.99
$159.99
$159.99

Not enough listings with 30 days of checks to summarise a change — 2 of 7 qualify so far.

7

Active listings

0

Independent lab tests

$78–$209

Observed price range

3

Known aliases

Understand this compound

What is Mazdutide?

In clinical trials

A weight-loss molecule that hits two hormone systems at once — a fullness signal plus one that raises energy burn. Approved in China, but not in the US.

Weight & metabolic
⚠

Good to know: Approved only in China; it is not FDA-approved, so it is unregulated in the US/global grey market and has less long-term safety data outside Chinese trial populations.

How does Mazdutide work?

The science

A dual GLP-1/glucagon receptor co-agonist, in the same mechanistic class as survodutide; reduces appetite and increases energy expenditure via combined incretin and glucagon receptor activation.

Mechanism of action from published research — how the molecule behaves, not a claim about any product or any human-use effect.

What is Mazdutide researched for?

Studied for obesity/weight management and type-2 diabetes glycemic control.

  • Weight & metabolicStudied in weight, appetite, blood-sugar, and fat-metabolism research.
How far has the research gone?

In clinical trials in the US (Phase 2); approved in China by the NMPA (2025-2026) for weight management and glycemic control, but not FDA-approved.

Where the science stands — an approved drug is not the same as the research-grade material a vendor sells, which is unregulated regardless.

What should I check before buying?
  • Independent purity. Look for a third-party COA (Janoshik or MZ) showing a measured purity — not just a number the vendor typed.
  • Batch match. The strongest evidence is a certificate for the exact batch you’ll receive, attributed to this vendor — check the cross-verification on the listing.
  • Vendor reputation. See how the vendor is talked about in the community before trusting a new name.

Research context only — VialGrade never gives dosing, medical, or human-use guidance.

Current market

The Mazdutide market

Every Mazdutide listing we track — 7 in all. The standout picks first where the evidence supports them, then the full table, ranked by what a milligram really costs wherever the vendor published a strength we can read.

Open full market

Compare by real cost

Every Mazdutide listing, cheapest per mg first

Sticker prices hide the size, so listings are ranked by what a milligram actually costs — with independently tested purity where it exists. All 7 are here: the last 1 is a listing whose vendor never published a strength we can read, so it has no per-mg figure to sort on.

#VendorSizePricePer mgTested purityReal $/active mg
1Umbrella Labs20mg total20 Milligrams Vial each$200$10.00/mg——View
2Bluum PeptidesUnavailable10mg total$119$11.9/mg——View
3Umbrella Labs10mg total$120$12.0/mg——View
4Modern AminosUnavailable5mg total$78$15.6/mg——View
5Bluum Peptides5mg total$79$15.8/mg——View
6Purerawz12mg total$209$17.4/mg——View
Listed, but not rankable — no published strength to price per mg
—Purerawz1 vial$116no size published——View

Open the full Mazdutide market

Real $/active mg divides the price-per-mg by the measured purity — the honest cost of the actual peptide, so a 90%-pure vial isn’t compared as if it were 99%. Too cheap? flags a listing far below the market rate — often underdosing or a fake, not a deal. The crown marks the cheapest non-outlier; best value marks the lowest real cost per active mg. A vendor shown as Unavailable or Low stock is priced here but not currently buyable.

What the research says

Scientific evidence & regulatory status

What the published literature actually shows about Mazdutide — separate from any vendor’s marketing. Each finding links to its paper. This is education, not medical or dosing advice.

Regulatory status

No FDA-approved drug

Not FDA-approved. China's NMPA approved mazdutide in June 2025 for chronic weight management, adding a type 2 diabetes indication in September 2025; it holds no US or EU marketing authorization. FDA has warned a US seller that offering it online makes it an unapproved new drug.

US legal status

Investigational drug — not approved, under FDA scrutiny

This is an investigational dual-agonist still in trials. It has no FDA approval for any use, is not a supplement, and the FDA is actively watching the GLP-1-class “research” market. Sold research-use-only; marketing or using it as a drug is not lawful.

Read the full US law →

General information, not legal or medical advice. VialGrade sells nothing and encourages no human use.

Research notes aren’t product proof

Research summaries describe published literature and market data only. They do not establish the identity, quality, safety, or legal status of any listed physical product.