Live data — every record is aggregated from real public sources. VialGrade never sells; it links out to the vendor.
VialGrade
All compounds
Growth hormone secretagogue
Live data

MK-677

Growth hormone supportMuscle & performance

An orally-active ghrelin mimetic (Ibutamoren) widely discussed in growth-hormone and body-composition research — a non-injectable favorite.

IbutamorenIbutamoren mesylateMK677L-163191

Get told when a price moves or a lab test changes.

Observed median price

$75

0.0 % · 30d
Every observation
DateObserved
$68.98
$142.96
$75.00
$75.00
$70.99
$75.00
$75.00
$70.99
$75.00
$75.00
$79.00
$79.99
$75.00
$70.99
$70.99
$70.99
$70.99
$70.99
$70.99
$70.99
$70.99
$70.99
$70.99
$70.99
$70.99
$70.99
$70.99
$70.99
$70.99
$70.99
$70.99
$70.99
$70.99
$70.99
$70.99
$70.47
$70.99

Median of 17 listings' 30-day changes; 23 excluded for insufficient history.

40

Active listings

2 · 99.9%

Independent lab tests

$33–$640

Observed price range

5

Known aliases

Read from the certificate, not re-measured by VialGrade. Purity is not a grade. Purity vs grade

Understand this compound

What is MK-677?

In clinical trialsa.k.a. Ibutamoren

A pill — not an injection — that mimics the hunger hormone to raise growth hormone and IGF-1. Big-pharma trials found raised blood sugar and no strength benefit, so it was shelved and never approved.

Growth hormone supportMuscle & performance
⚠

Good to know: Trials found increased fasting glucose and, in one elderly trial, more congestive heart failure events, without a functional strength benefit; it is not FDA-approved for any use.

How does MK-677 work?

The science

An orally active, non-peptide ghrelin receptor (GHSR-1a) agonist; increases GH and IGF-1 secretion and stimulates hypothalamic appetite pathways.

Mechanism of action from published research — how the molecule behaves, not a claim about any product or any human-use effect.

What is MK-677 researched for?

Studied for GH/IGF-1 restoration in aging and muscle-wasting (cachexia) research, sleep quality, and body composition.

  • Growth hormone supportStudied for how it interacts with the body's own growth-hormone axis in research settings.
  • Muscle & performanceStudied in muscle-growth, repair, and physical-performance research.
How far has the research gone?

In clinical trials, discontinued; Merck-sponsored Phase 2/3 trials were completed but no NDA was ever filed after mixed results.

Where the science stands — an approved drug is not the same as the research-grade material a vendor sells, which is unregulated regardless.

What should I check before buying?
  • Independent purity. Look for a third-party COA (Janoshik or MZ) showing a measured purity — not just a number the vendor typed.
  • Batch match. The strongest evidence is a certificate for the exact batch you’ll receive, attributed to this vendor — check the cross-verification on the listing.
  • Vendor reputation. See how the vendor is talked about in the community before trusting a new name.

Research context only — VialGrade never gives dosing, medical, or human-use guidance.

Current market

The MK-677 market

Every MK-677 listing we track — 40 in all. The standout picks first where the evidence supports them, then the full table, ranked by what a milligram really costs wherever the vendor published a strength we can read.

Open full market

Compare by real cost

Every MK-677 listing, cheapest per mg first

Sticker prices hide the size, so listings are ranked by what a milligram actually costs — with independently tested purity where it exists. All 40 are here: the last 19 are listings whose vendor never published a strength we can read, so they have no per-mg figure to sort on.

#VendorSizePricePer mgTested purityReal $/active mg
1Purerawz27.25g total50ml/545mg per ml/27.25g each$143$0.0052/mg · too cheap?—$0.0052/mgbest valueView
2Behemoth LabzUnavailable9.3g total60ct/155mg per capsule/9.3g each$98$0.01/mg · too cheap?—$0.01/mgView
3Behemoth LabzUnavailable4.65g total30ct/155mg per capsule / 4.6g each$51$0.01/mg · too cheap?—$0.01/mgView
4Nootropic SourceUnavailable10g total10 Grams each$300$0.03/mg · too cheap?—$0.03/mgView
5Nootropic Source5g total5 Grams each$200$0.04/mg · too cheap?—$0.04/mgView
6Sports Technology Labs2g total2Grams each$98$0.05/mg99.9%$0.05/mgView
7Chemyo1g total1g each$60$0.06/mg100.0%$0.06/mgView
8Chemyo1.25g total25mg each$80$0.06/mg100.0%$0.06/mgView
9Umbrella Labs1g total$71$0.07/mg—$0.07/mgView
10PurerawzUnavailable1.8g totalTablets · 90mg per tablet/20ct/1.8g each$130$0.07/mg—$0.07/mgView

Open the full MK-677 market

Real $/active mg divides the price-per-mg by the measured purity — the honest cost of the actual peptide, so a 90%-pure vial isn’t compared as if it were 99%. Too cheap? flags a listing far below the market rate — often underdosing or a fake, not a deal. The crown marks the cheapest non-outlier; best value marks the lowest real cost per active mg. A vendor shown as Unavailable or Low stock is priced here but not currently buyable.

Independent testing

MK-677 — independent lab tests

Real, publicly verifiable third-party tests. Purity is read from the certificate itself. A test reflects one lab’s result for one submitted batch — not a guarantee that every vial matches.

How does this data get here?

Every record below is a real certificate of analysis, gathered two ways: from the public verification feeds that independent labs (like Janoshik) publish, and from the certificates vendors post on their own product pages. We open each certificate document and read the measured purity, content, batch, and date directly off it — a scraper can’t read a number printed inside an image, so this is done by machine vision, then recorded here with a link back to the original.

Nothing here is typed in by a vendor or invented by us. Where a certificate is missing, we say so rather than filling the gap.

We re-check the lab feed, too. A “still listed” tag means the certificate is currently public in Janoshik’s database — we re-verify against the live feed and stamp the date. If a cert is later pulled, the tag flips. It’s a freshness check on the same source, not a second independent opinion.

What a certificate does & doesn’t prove

Three different questions. Purity (“how clean?”), identity (“is it the right molecule?”, a mass-spec test), and content (“did I get the labeled mg?”) are separate. A vial can be 99% pure and still be the wrong peptide, or the right peptide underdosed. We flag the measured dose against the label above; underdosing is the most common real fraud.

Who submitted the sample matters. Most of these are vendor-submitted — the seller chose which vial to send, so one good certificate doesn’t prove every batch is the same. The gold standard is a blind test, where a buyer sends a vial they bought as a normal customer. Same label doesn’t prove same product; same batch number doesn’t prove same batch.

100.0%

highest tested purity

CertificateManufacturerBatchPurityContent / doseLab
Certificate of analysisChemyoBA2200100.00%—Nutri Analytical Testing Laboratories View
Certificate of analysisSports Technology Labs2026-05-0499.87%—MZ Biolabs View

Tested batches

Batch test records for MK-677

The full test history for one batch — who picked the sample, who tested it, and what came back. It describes the vials that were tested, never every vial they sold.

All batch records

What the research says

Scientific evidence & regulatory status

What the published literature actually shows about MK-677 — separate from any vendor’s marketing. Each finding links to its paper. This is education, not medical or dosing advice.

Regulatory status

No FDA-approved drug

Not FDA-approved. FDA placed ibutamoren mesylate in category 2 (significant safety risks) for compounding, citing a trial stopped early over a congestive-heart-failure signal, and its advisory committee voted 13-1 against adding it to the compounding list in 2024. FDA also excludes ibutamoren from the dietary-supplement definition; WADA prohibits it at all times as a growth-hormone secretagogue (S2.2.4).

US legal statusBanned in drug-tested sport (WADA/USADA)

Research-use-only — not FDA-approved

Sold “for research use only,” this compound is not FDA-approved for human use and has not been evaluated for safety, purity, or sterility in people. It is generally not a scheduled controlled substance, so buying it as a research chemical is typically not itself a drug crime — but marketing or using it as a drug is not lawful, and it is not a dietary supplement.

Read the full US law →

General information, not legal or medical advice. VialGrade sells nothing and encourages no human use.

Research notes aren’t product proof

Research summaries describe published literature and market data only. They do not establish the identity, quality, safety, or legal status of any listed physical product.