NAD+
The NAD+ coenzyme central to cellular energy and a cornerstone of longevity research.
Get told when a price moves or a lab test changes.
Observed median price
$59
Every observation
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| $49.00 | |
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| $39.95 | |
| $39.95 | |
| $49.00 |
Median of 5 listings' 30-day changes; 2 excluded for insufficient history.
7
Active listings
0
Independent lab tests
$25–$480
Observed price range
3
Known aliases
Understand this compound
What is NAD+?
In clinical trialsa.k.a. Nicotinamide adenine dinucleotide (precursors: NMN, NR)A molecule every cell uses to turn food into energy and repair DNA. Levels fall with age, so raising them — usually via the precursors NMN or NR — is a cornerstone of longevity research.
Good to know: Raising blood NAD+ levels is well established, but translation into meaningful clinical benefit beyond subjective effects remains weakly supported in adequately powered trials.
How does NAD+ work?
The science
A coenzyme central to redox reactions, ATP production, and DNA repair; supplementation (typically via precursors like NMN or NR) aims to raise intracellular NAD+ levels that decline with age.
Mechanism of action from published research — how the molecule behaves, not a claim about any product or any human-use effect.
What is NAD+ researched for?
Studied for metabolic health, cellular energy production, and age-related decline broadly.
- Longevity & anti-agingStudied in aging, cellular-senescence, and mitochondrial-function research.
How far has the research gone?
In clinical trials — more than a dozen human trials of NAD+ precursors confirm they safely raise NAD+ levels, though evidence for clinically meaningful health benefits is limited and mixed.
Where the science stands — an approved drug is not the same as the research-grade material a vendor sells, which is unregulated regardless.
What should I check before buying?
- Independent purity. Look for a third-party COA (Janoshik or MZ) showing a measured purity — not just a number the vendor typed.
- Batch match. The strongest evidence is a certificate for the exact batch you’ll receive, attributed to this vendor — check the cross-verification on the listing.
- Vendor reputation. See how the vendor is talked about in the community before trusting a new name.
Research context only — VialGrade never gives dosing, medical, or human-use guidance.
Current market
The NAD+ market
Every NAD+ listing we track — 7 in all. The standout picks first where the evidence supports them, then the full table, ranked by what a milligram really costs wherever the vendor published a strength we can read.
Open full marketNAD+ (Nicotinamide Adenine Dinucleotide) 100 mg NAD+ 100mg: KIT (10 vials)
Swiss ChemsC-
$480$0.48/mg+389% vs median
Lowest price per mg that isn't flagged as suspiciously cheap.
In stockChecked 10 hours ago
NAD+ (Nicotinamide Adenine Dinucleotide) – Powder, 10 grams 1 vial
Swiss ChemsC-
$25$0.0025/mg-97% vs median
Ranked #1 of 4 listings by price per milligram.
In stockChecked 10 hours ago
NAD+ (Nicotinamide Adenine Dinucleotide) 500MG (Lyophilized)
Modern AminosB
$49$0.10/mg
Ranked #2 of 4 listings by price per milligram.
In stockChecked 10 hours ago
NAD+ (Nicotinamide Adenine Dinucleotide) 100 mg
Swiss ChemsC-
$48$0.48/mg+389% vs median
Ranked #4 of 4 listings by price per milligram.
UnavailableChecked 1 month ago
Compare by real cost
Every NAD+ listing, cheapest per mg first
Sticker prices hide the size, so listings are ranked by what a milligram actually costs — with independently tested purity where it exists. All 7 are here: the last 3 are listings whose vendor never published a strength we can read, so they have no per-mg figure to sort on.
| # | Vendor | Size | Price | Per mg | Tested purity | Real $/active mg | |
|---|---|---|---|---|---|---|---|
| 1 | Swiss Chems | 10g total | $25 | $0.0025/mg · too cheap? | — | — | View |
| 2 | Modern Aminos | 500mg total | $49 | $0.10/mg · too cheap? | — | — | View |
| 3 | Swiss Chems | 1g totalNAD+ 100mg: KIT (10 vials) each | $480 | $0.48/mg | — | — | View |
| 4 | Swiss ChemsUnavailable | 100mg total | $48 | $0.48/mg | — | — | View |
| Listed, but not rankable — no published strength to price per mg | |||||||
| — | Nootropic SourceUnavailable | 1 vial | $40 | no size published | — | — | View |
| — | Behemoth LabzUnavailable | 1 vial | $66 | no size published | — | — | View |
| — | Modern Aminos | 200MG/ML (20ML) | $69 | no size published | — | — | View |
Real $/active mg divides the price-per-mg by the measured purity — the honest cost of the actual peptide, so a 90%-pure vial isn’t compared as if it were 99%. Too cheap? flags a listing far below the market rate — often underdosing or a fake, not a deal. The crown marks the cheapest non-outlier; best value marks the lowest real cost per active mg. A vendor shown as Unavailable or Low stock is priced here but not currently buyable.
What the research says
Scientific evidence & regulatory status
What the published literature actually shows about NAD+ — separate from any vendor’s marketing. Each finding links to its paper. This is education, not medical or dosing advice.
Regulatory status
No FDA-approved drug
NAD+ precursors NR and NMN are sold as dietary supplements (NR/Niagen has US NDI/GRAS status); NAD+ itself and injectable/IV NAD+ are not FDA-approved drugs
Honest overall read
The precursors NR and NMN reliably and safely raise blood NAD+ in humans in short RCTs, but downstream clinical benefits are modest, mixed, and often confounded with exercise; there is no human evidence that NAD+ precursors extend lifespan, and IV/injectable NAD+ has little rigorous trial support.
In 140 healthy overweight adults, oral nicotinamide riboside (100/300/1000 mg/day for 8 weeks) raised blood NAD+ dose-dependently (up to ~142% at 1000 mg) with no serious adverse events and no LDL/homocysteine elevation.
Confirms NAD+ can be raised safely short-term, but the trial measured biomarkers, not disease, aging, or longevity outcomes.
read the sourceIn 48 amateur runners, 6 weeks of NMN (300/600/1200 mg/day) alongside exercise training raised oxygen uptake and ventilatory thresholds more than placebo.
Benefit appeared only combined with an exercise program and was not attributable to NMN alone; sample small and short.
read the sourceCommonly researched together
Often stacked with NAD+
Compounds the research community frequently discusses alongside NAD+. Not a protocol or a recommendation — a starting point for what to read about next.
Epitalon
Longevity peptide
A pineal tetrapeptide famous in longevity and telomere research — the flagship 'anti-aging' peptide.
MOTS-c
Mitochondrial peptide
A mitochondrial peptide studied in metabolism, exercise-capacity, and longevity research.
Research-use-only — not FDA-approved
Sold “for research use only,” this compound is not FDA-approved for human use and has not been evaluated for safety, purity, or sterility in people. It is generally not a scheduled controlled substance, so buying it as a research chemical is typically not itself a drug crime — but marketing or using it as a drug is not lawful, and it is not a dietary supplement.
General information, not legal or medical advice. VialGrade sells nothing and encourages no human use.
Research notes aren’t product proof
Research summaries describe published literature and market data only. They do not establish the identity, quality, safety, or legal status of any listed physical product.