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Coenzyme / metabolic
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NAD+

Longevity & anti-aging

An endogenous pyridine-nucleotide coenzyme (nicotinamide adenine dinucleotide) central to cellular redox reactions.

Nicotinamide adenine dinucleotideNAD plus

Observed median price

$44

0%

4

Active listings

0

Independent lab tests

$25–$66

Observed price range

3

Known aliases

Understand this compound

What is NAD+?

In clinical trialsa.k.a. Nicotinamide adenine dinucleotide (precursors: NMN, NR)

The NAD+ coenzyme central to cellular energy and a cornerstone of longevity research.

Longevity & anti-aging

Good to know: Raising blood NAD+ levels is well established, but translation into meaningful clinical benefit beyond subjective effects remains weakly supported in adequately powered trials.

How does NAD+ work?

A coenzyme central to redox reactions, ATP production, and DNA repair; supplementation (typically via precursors like NMN or NR) aims to raise intracellular NAD+ levels that decline with age.

Mechanism of action from published research — how the molecule behaves, not a claim about any product or any human-use effect.

What is NAD+ researched for?

Studied for metabolic health, cellular energy production, and age-related decline broadly.

  • Longevity & anti-agingStudied in aging, cellular-senescence, and mitochondrial-function research.
How far has the research gone?

In clinical trials — more than a dozen human trials of NAD+ precursors confirm they safely raise NAD+ levels, though evidence for clinically meaningful health benefits is limited and mixed.

Where the science stands — an approved drug is not the same as the research-grade material a vendor sells, which is unregulated regardless.

What should I check before buying?
  • Independent purity. Look for a third-party COA (Janoshik or MZ) showing a measured purity — not just a number the vendor typed.
  • Batch match. The strongest evidence is a certificate for the exact batch you’ll receive, attributed to this vendor — check the cross-verification on the listing.
  • Vendor reputation. See how the vendor is talked about in the community before trusting a new name.

Research context only — VialGrade never gives dosing, medical, or human-use guidance.

US legal status

Research-use-only — not FDA-approved

Sold “for research use only,” this compound is not FDA-approved for human use and has not been evaluated for safety, purity, or sterility in people. It is generally not a scheduled controlled substance, so buying it as a research chemical is typically not itself a drug crime — but marketing or using it as a drug is not lawful, and it is not a dietary supplement.

Read the full US legal overview →

General information, not legal or medical advice. VialGrade sells nothing and encourages no human use.

Compare by real cost

Cheapest NAD+, by price per mg

Vials come in different sizes, so the sticker price lies. This ranks every listing by what a milligram actually costs — with independent test purity where we have it.

#VendorSizePricePer mgTested purityReal $/active mg
1Swiss Chems10000mg total1 vial each$25$0.00/mgView
2Swiss Chems100mg total$48$0.48/mgView

Real $/active mg divides the price-per-mg by the measured purity — the honest cost of the actual peptide, so a 90%-pure vial isn’t compared as if it were 99%. Too cheap? flags a listing far below the market rate — often underdosing or a fake, not a deal. The crown marks the cheapest non-outlier; best value marks the lowest real cost per active mg.

Current market

All NAD+ listings

Commonly researched together

Often stacked with NAD+

Compounds the research community frequently discusses alongside NAD+. Not a protocol or a recommendation — a starting point for what to read about next.

Research notes aren’t product proof

Research summaries describe published literature and market data only. They do not establish the identity, quality, safety, or legal status of any listed physical product.