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Nootropic peptide
Live data

P21

Cognitive & mood

A synthetic peptidomimetic derived from a biologically active region of ciliary neurotrophic factor (CNTF).

P021P-21

Observed median price

$62

0%

1

Active listings

0

Independent lab tests

$62–$62

Observed price range

3

Known aliases

Understand this compound

What is P21?

Preclinical / animal onlya.k.a. TFP5 (related fragment)

A CNTF-derived peptidomimetic studied in neurogenesis research.

Cognitive & mood

Good to know: Research is confined to animal models of stroke and neurodegeneration; no human safety or efficacy data exist.

How does P21 work?

A peptide derived from the CDK5-activating cofactor p35, designed to inhibit pathological CDK5/p25 hyperactivity implicated in neuronal apoptosis after injury or in neurodegeneration.

Mechanism of action from published research — how the molecule behaves, not a claim about any product or any human-use effect.

What is P21 researched for?

Studied for neuroprotection in ischemic stroke and neurodegenerative disease models, including Alzheimer's and Parkinson's.

  • Cognitive & moodStudied in memory, focus, mood, and neuroprotection research.
How far has the research gone?

Preclinical / animal research — efficacy shown in rodent stroke and Parkinson's models (often via the related peptide 'TFP5'), with no identified human trials.

Where the science stands — an approved drug is not the same as the research-grade material a vendor sells, which is unregulated regardless.

What should I check before buying?
  • Independent purity. Look for a third-party COA (Janoshik or MZ) showing a measured purity — not just a number the vendor typed.
  • Batch match. The strongest evidence is a certificate for the exact batch you’ll receive, attributed to this vendor — check the cross-verification on the listing.
  • Vendor reputation. See how the vendor is talked about in the community before trusting a new name.

Research context only — VialGrade never gives dosing, medical, or human-use guidance.

US legal status

Research-use-only — not FDA-approved

Sold “for research use only,” this compound is not FDA-approved for human use and has not been evaluated for safety, purity, or sterility in people. It is generally not a scheduled controlled substance, so buying it as a research chemical is typically not itself a drug crime — but marketing or using it as a drug is not lawful, and it is not a dietary supplement.

Read the full US legal overview →

General information, not legal or medical advice. VialGrade sells nothing and encourages no human use.

Current market

All P21 listings

P21 (P021) 1 vialPureRawz
C-Grade C-
Cognitive & mood

$62

Vendor catalog No lab testLive data

Availability

In stock

Last checked

3 hours ago

Research notes aren’t product proof

Research summaries describe published literature and market data only. They do not establish the identity, quality, safety, or legal status of any listed physical product.