PT-141
Bremelanotide, a melanocortin peptide studied in libido and sexual-function research.
Get told when a price moves or a lab test changes.
Observed median price
$43
Every observation
| Date | Observed |
|---|---|
| $44.99 | |
| $83.19 | |
| $49.95 | |
| $49.95 | |
| $49.95 | |
| $49.95 | |
| $49.95 | |
| $49.97 | |
| $47.00 | |
| $47.00 | |
| $47.00 | |
| $47.00 | |
| $47.00 | |
| $45.00 | |
| $45.00 | |
| $45.00 | |
| $47.00 | |
| $47.00 | |
| $47.00 | |
| $45.00 | |
| $45.00 | |
| $45.00 | |
| $45.00 | |
| $47.00 | |
| $47.00 | |
| $47.00 | |
| $45.00 | |
| $45.00 | |
| $45.00 | |
| $45.00 | |
| $47.00 | |
| $45.00 | |
| $45.00 | |
| $43.50 | |
| $44.00 | |
| $44.00 | |
| $43.00 |
Median of 12 listings' 30-day changes; 20 excluded for insufficient history.
32
Active listings
3 · 99.9%
Independent lab tests
$22–$500
Observed price range
4
Known aliases
Read from the certificate, not re-measured by VialGrade. Purity is not a grade. Purity vs grade
Understand this compound
What is PT-141?
FDA-approved moleculea.k.a. Bremelanotide, VyleesiThe 'desire molecule' — it works on arousal circuits in the brain rather than on blood flow. Approved as Vyleesi for low sexual desire in premenopausal women.
Good to know: FDA approval is specific to premenopausal women with acquired, generalized HSDD; use in men or for other purposes is off-label, and it commonly causes nausea and can raise blood pressure.
How does PT-141 work?
The science
A cyclic heptapeptide melanocortin agonist, derived from the same alpha-MSH scaffold as the melanotans, that selectively activates MC3/MC4 receptors in the hypothalamus and limbic system to act on central sexual-desire pathways rather than local blood flow.
Mechanism of action from published research — how the molecule behaves, not a claim about any product or any human-use effect.
What is PT-141 researched for?
Studied for hypoactive sexual desire disorder in women and, via central mechanisms, erectile dysfunction in men.
- Tanning & libidoStudied in melanocortin research — skin pigmentation and related pathways.
- Reproductive & hormonalStudied in reproductive-hormone and endocrine-axis research.
How far has the research gone?
FDA-approved (for HSDD in premenopausal women) — approved as Vyleesi in 2019 following two Phase 3 trials.
Where the science stands — an approved drug is not the same as the research-grade material a vendor sells, which is unregulated regardless.
What should I check before buying?
- Independent purity. Look for a third-party COA (Janoshik or MZ) showing a measured purity — not just a number the vendor typed.
- Batch match. The strongest evidence is a certificate for the exact batch you’ll receive, attributed to this vendor — check the cross-verification on the listing.
- Vendor reputation. See how the vendor is talked about in the community before trusting a new name.
Research context only — VialGrade never gives dosing, medical, or human-use guidance.
Current market
The PT-141 market
Every PT-141 listing we track — 32 in all. The standout picks first where the evidence supports them, then the full table, ranked by what a milligram really costs wherever the vendor published a strength we can read.
Open full marketPT-141 (Bremelanotide) 10 mg
Sports Technology LabsA
$26$2.60/mg-31% vs median
Lowest price per mg that isn't flagged as suspiciously cheap.
In stockChecked 10 hours ago
PT-141 BREMELANOTIDE PEPTIDE 10MG VIAL 40MG
Umbrella LabsC-
$41$1.02/mg-73% vs median
Lowest real cost per active mg — price divided by measured purity.
In stockChecked 10 hours ago
PT-141 10mg 10mg
EZ PeptidesA
$44$4.40/mg+17% vs median
Independently tested at 99.9%.
In stockChecked 10 hours ago
PT-141 (Bremelanotide), 10mg
Swiss ChemsC-
$50$5.00/mg+33% vs median
The most recently re-verified listing on this market.
UnavailableChecked 8 hours ago
PT-141 10mg 10-vial kit
Chameleon PeptidesA
$294$2.94/mg-22% vs median
Ranked #3 of 24 listings by price per milligram.
In stockChecked 4 days ago
Compare by real cost
Every PT-141 listing, cheapest per mg first
Sticker prices hide the size, so listings are ranked by what a milligram actually costs — with independently tested purity where it exists. All 32 are here: the last 8 are listings whose vendor never published a strength we can read, so they have no per-mg figure to sort on.
| # | Vendor | Size | Price | Per mg | Tested purity | Real $/active mg | |
|---|---|---|---|---|---|---|---|
| 1 | Umbrella Labs | 40mg total | $41 | $1.02/mg · too cheap? | — | $1.03/mgbest value | View |
| 2 | Sports Technology Labs | 10mg total | $26 | $2.60/mg | 99.9% | $2.60/mg | View |
| 3 | Chameleon Peptides | 100mg total10-vial kit each | $294 | $2.94/mg | 99.9% | $2.94/mg | View |
| 4 | Umbrella Labs | 40mg total | $130 | $3.25/mg | — | $3.25/mg | View |
| 5 | Bluum Peptides | 10mg total | $35 | $3.50/mg | — | $3.50/mg | View |
| 6 | Ion PeptideUnavailable | 30mg total | $109 | $3.63/mg | — | $3.64/mg | View |
| 7 | Ion Peptide | 10mg total | $37 | $3.70/mg | — | $3.70/mg | View |
| 8 | Peptide Pros | 10mg total | $38 | $3.75/mg | — | $3.75/mg | View |
| 9 | Ascend Bio LabsUnavailable | 100mg total10MG / 10 Vials each | $400 | $4.00/mg | — | $4.00/mg | View |
| 10 | Modern Aminos | 10mg total | $41 | $4.10/mg | — | $4.10/mg | View |
| 11 | Ascend Bio LabsUnavailable | 30mg total10MG / 3 Vials each | $128 | $4.27/mg | — | $4.27/mg | View |
| 12 | Felix Chemical Supply | 10mg total | $43 | $4.30/mg | — | $4.30/mg | View |
| 13 | Core Peptides | 10mg total | $43 | $4.30/mg | — | $4.30/mg | View |
| 14 | Ez Peptides | 10mg total | $44 | $4.40/mg | 99.9% | $4.40/mg | View |
| 15 | Biotech Peptides | 10mg total | $45 | $4.50/mg | — | $4.50/mg | View |
| 16 | Simple PeptideUnavailable | 10mg total | $45 | $4.50/mg | — | $4.50/mg | View |
| 17 | Ascend Bio LabsUnavailable | 20mg total10MG / 2 Vials each | $90 | $4.50/mg | — | $4.50/mg | View |
| 18 | Ascension PeptidesUnavailable | 10mg total | $49 | $4.90/mg | — | $4.90/mg | View |
| 19 | Swiss ChemsUnavailable | 100mg totalPT-141 (Bremenalotide) · 10mg: KIT (10 vials) each | $500 | $5.00/mg | — | $5.00/mg | View |
| 20 | Swiss ChemsUnavailable | 10mg total | $50 | $5.00/mg | — | $5.00/mg | View |
| 21 | Ascend Bio LabsUnavailable | 10mg total | $52 | $5.20/mg | — | $5.21/mg | View |
| 22 | PurerawzUnavailable | 10mg total | $75 | $7.49/mg | — | $7.49/mg | View |
| 23 | PurerawzUnavailable | 10mg totalSublingual Tablets · 100mcg per tab/100ct/10mg each | $83 | $8.32/mg | — | $8.33/mg | View |
| 24 | Chameleon Peptides | 10mg total | $179 | $17.9/mg | 99.9% | $17.9/mg | View |
| Listed, but not rankable — no published strength to price per mg | |||||||
| — | Eternal Peptides | 1 vial | $22 | no size published | — | — | View |
| — | Nootropic Source | 1 vial | $25 | no size published | — | — | View |
| — | Cernum BiosciencesUnavailable | 1 vial | $45 | no size published | — | — | View |
| — | Nootropic Source | 1 vial | $50 | no size published | — | — | View |
| — | Vici Peptides | 1 vial | $67 | no size published | — | — | View |
| — | Behemoth LabzUnavailable | 1 vial | $73 | no size published | — | — | View |
| — | PurerawzUnavailable | 1 vial | $75 | no size published | — | — | View |
| — | PurerawzUnavailable | Nasal Spray · 10ml / 100mcg per spray / 10mg | $115 | no size published | — | — | View |
Real $/active mg divides the price-per-mg by the measured purity — the honest cost of the actual peptide, so a 90%-pure vial isn’t compared as if it were 99%. Too cheap? flags a listing far below the market rate — often underdosing or a fake, not a deal. The crown marks the cheapest non-outlier; best value marks the lowest real cost per active mg. A vendor shown as Unavailable or Low stock is priced here but not currently buyable.
Independent testing
PT-141 — independent lab tests
Real, publicly verifiable third-party tests. Purity is read from the certificate itself. A test reflects one lab’s result for one submitted batch — not a guarantee that every vial matches.
How does this data get here?
Every record below is a real certificate of analysis, gathered two ways: from the public verification feeds that independent labs (like Janoshik) publish, and from the certificates vendors post on their own product pages. We open each certificate document and read the measured purity, content, batch, and date directly off it — a scraper can’t read a number printed inside an image, so this is done by machine vision, then recorded here with a link back to the original.
Nothing here is typed in by a vendor or invented by us. Where a certificate is missing, we say so rather than filling the gap.
We re-check the lab feed, too. A “still listed” tag means the certificate is currently public in Janoshik’s database — we re-verify against the live feed and stamp the date. If a cert is later pulled, the tag flips. It’s a freshness check on the same source, not a second independent opinion.
What a certificate does & doesn’t prove
Three different questions. Purity (“how clean?”), identity (“is it the right molecule?”, a mass-spec test), and content (“did I get the labeled mg?”) are separate. A vial can be 99% pure and still be the wrong peptide, or the right peptide underdosed. We flag the measured dose against the label above; underdosing is the most common real fraud.
Who submitted the sample matters. Most of these are vendor-submitted — the seller chose which vial to send, so one good certificate doesn’t prove every batch is the same. The gold standard is a blind test, where a buyer sends a vial they bought as a normal customer. Same label doesn’t prove same product; same batch number doesn’t prove same batch.
99.9%
highest tested purity
Tested batches
Batch test records for PT-141
The full test history for one batch — who picked the sample, who tested it, and what came back. It describes the vials that were tested, never every vial they sold.
What the research says
Scientific evidence & regulatory status
What the published literature actually shows about PT-141 — separate from any vendor’s marketing. Each finding links to its paper. This is education, not medical or dosing advice.
Regulatory status
An approved drug exists — this is not it
Bremelanotide is FDA-approved as Vyleesi (NDA 210557, 2019) — a prescription autoinjector for acquired, generalized hypoactive sexual desire disorder in premenopausal women. 'PT-141' sold as research material is not that product.
Honest overall read
PT-141/bremelanotide has the strongest evidence base of the non-metabolic peptides here: two positive placebo-controlled Phase 3 RCTs supporting a real but modest effect on sexual desire in premenopausal women with HSDD, leading to FDA approval; it is not an approved general or male 'libido' drug.
In two identical randomized, double-blind, placebo-controlled Phase 3 trials (RECONNECT), bremelanotide significantly improved sexual desire (integrated FSFI-desire change 0.35, P<.001) and reduced desire-related distress versus placebo in premenopausal women with HSDD.
Common adverse events were nausea, flushing, and headache; most mild-to-moderate, but nausea led some participants to discontinue.
read the sourceA 52-week open-label extension of the RECONNECT trials reported sustained improvement in HSDD symptoms with no new safety signals over long-term use.
Open-label extension (no placebo comparator in this phase); transient blood-pressure increases and focal hyperpigmentation are recognized class effects.
read the sourceCommonly researched together
Often stacked with PT-141
Compounds the research community frequently discusses alongside PT-141. Not a protocol or a recommendation — a starting point for what to read about next.
Research-use-only — not FDA-approved
Sold “for research use only,” this compound is not FDA-approved for human use and has not been evaluated for safety, purity, or sterility in people. It is generally not a scheduled controlled substance, so buying it as a research chemical is typically not itself a drug crime — but marketing or using it as a drug is not lawful, and it is not a dietary supplement.
General information, not legal or medical advice. VialGrade sells nothing and encourages no human use.
Research notes aren’t product proof
Research summaries describe published literature and market data only. They do not establish the identity, quality, safety, or legal status of any listed physical product.