Semax
A Russian nootropic peptide studied in focus, memory, and neuroprotection research. Often paired with Selank.
Get told when a price moves or a lab test changes.
Observed median price
$60
Every observation
| Date | Observed |
|---|---|
| $43.99 | |
| $68.80 | |
| $34.00 | |
| $49.99 | |
| $56.63 | |
| $55.00 | |
| $58.25 | |
| $47.00 | |
| $58.25 | |
| $60.00 | |
| $59.99 | |
| $60.00 | |
| $60.00 | |
| $58.25 | |
| $60.00 | |
| $59.13 | |
| $60.00 | |
| $58.25 | |
| $60.00 | |
| $58.25 | |
| $59.13 | |
| $60.00 | |
| $59.13 | |
| $59.13 | |
| $59.13 | |
| $59.13 | |
| $60.00 | |
| $60.00 | |
| $60.00 | |
| $60.00 | |
| $60.00 | |
| $64.20 | |
| $64.20 | |
| $60.00 | |
| $60.00 | |
| $58.25 | |
| $60.00 | |
| $59.13 | |
| $58.25 |
Median of 13 listings' 30-day changes; 33 excluded for insufficient history.
45
Active listings
9 · 99.3%
Independent lab tests
$19–$740
Observed price range
2
Known aliases
Read from the certificate, not re-measured by VialGrade. Purity is not a grade. Purity vs grade
Understand this compound
What is Semax?
Widely studieda.k.a. SemaxA focus-and-recovery molecule from Russian research — a fragment of a stress hormone repurposed to boost the brain's own growth factors. Prescribed in Russia after strokes; often paired with Selank.
Good to know: Regulatory approval and most clinical data are confined to Russia and published largely in Russian-language journals, limiting independent verification by Western standards.
How does Semax work?
The science
A synthetic ACTH(4-10) fragment analog that upregulates BDNF/NGF expression via CREB pathway activation and modulates dopaminergic and serotonergic signaling.
Mechanism of action from published research — how the molecule behaves, not a claim about any product or any human-use effect.
What is Semax researched for?
Studied for cognitive enhancement, ischemic stroke recovery, and general neuroprotection.
- Cognitive & moodStudied in memory, focus, mood, and neuroprotection research.
How far has the research gone?
Widely studied — approved as a prescription drug in Russia/CIS for stroke and age-related cognitive decline since the early 2000s, but never evaluated in large randomized Western trials.
Where the science stands — an approved drug is not the same as the research-grade material a vendor sells, which is unregulated regardless.
What should I check before buying?
- Independent purity. Look for a third-party COA (Janoshik or MZ) showing a measured purity — not just a number the vendor typed.
- Batch match. The strongest evidence is a certificate for the exact batch you’ll receive, attributed to this vendor — check the cross-verification on the listing.
- Vendor reputation. See how the vendor is talked about in the community before trusting a new name.
Research context only — VialGrade never gives dosing, medical, or human-use guidance.
Current market
The Semax market
Every Semax listing we track — 45 in all. The standout picks first where the evidence supports them, then the full table, ranked by what a milligram really costs wherever the vendor published a strength we can read.
Open full marketSemax 30mg
Peptide ProsC+
$58$1.94/mg-45% vs median
Lowest price per mg that isn't flagged as suspiciously cheap.
In stockChecked 9 hours ago
N-ACETYL SEMAX AMIDATE PEPTIDE LIQUID SPRAY 15ML BOTTLE 90 Milligrams Liquid Spray
Umbrella LabsC-
$100$1.11/mg-68% vs median
Lowest real cost per active mg — price divided by measured purity.
In stockChecked 2 days ago
N-Acetyl Semax Amidate 10mg
EZ PeptidesA
$44$4.40/mg+26% vs median
Independently tested at 100.0%.
In stockChecked 9 hours ago
Semax (10MG)
Ascension Peptides
$50$5.00/mg+43% vs median
The most recently re-verified listing on this market.
UnavailableChecked 8 hours ago
Semax Peptide 30mg
Nootropic SourceC-
$35$1.17/mg-67% vs median
Ranked #2 of 38 listings by price per milligram.
In stockChecked 9 hours ago
Compare by real cost
Every Semax listing, cheapest per mg first
Sticker prices hide the size, so listings are ranked by what a milligram actually costs — with independently tested purity where it exists. All 45 are here: the last 7 are listings whose vendor never published a strength we can read, so they have no per-mg figure to sort on.
| # | Vendor | Size | Price | Per mg | Tested purity | Real $/active mg | |
|---|---|---|---|---|---|---|---|
| 1 | Umbrella Labs | 90mg total90 Milligrams Liquid Spray each | $100 | $1.11/mg · too cheap? | — | $1.12/mgbest value | View |
| 2 | Nootropic Source | 30mg total | $35 | $1.17/mg · too cheap? | — | $1.17/mg | View |
| 3 | Nootropic Source | 60mg total600mcg+ per spray (10mL bottle @ 6mg per mL) each | $70 | $1.17/mg · too cheap? | — | $1.18/mg | View |
| 4 | Nootropic Source | 20mg total200mcg+ per spray (10mL bottle @ 2mg per mL) each | $30 | $1.50/mg · too cheap? | — | $1.51/mg | View |
| 5 | Peptide Pros | 30mg total | $58 | $1.94/mg | — | $1.96/mg | View |
| 6 | Nootropic Source | 30mg total300mcg+ per spray (10mL bottle @ 3mg per mL) each | $60 | $2.00/mg | — | $2.01/mg | View |
| 7 | Biotech Peptides | 25mg total | $53 | $2.12/mg | — | $2.14/mg | View |
| 8 | Umbrella Labs | 30mg total | $70 | $2.33/mg | — | $2.35/mg | View |
| 9 | Umbrella Labs | 30mg total30 Milligrams Liquid Spray each | $70 | $2.33/mg | — | $2.35/mg | View |
| 10 | Core Peptides | 25mg total | $60 | $2.40/mg | — | $2.42/mg | View |
| 11 | Swiss ChemsUnavailable | 300mg totalKIT (10 vials) each | $740 | $2.46/mg | — | $2.48/mg | View |
| 12 | Swiss Chems | 30mg total | $74 | $2.47/mg | — | $2.48/mg | View |
| 13 | Ion PeptideUnavailable | 30mg total | $99 | $3.30/mg | — | $3.32/mg | View |
| 14 | Behemoth Labz | 30mg total | $100 | $3.34/mg | — | $3.37/mg | View |
| 15 | Behemoth LabzUnavailable | 60mg total | $201 | $3.34/mg | — | $3.37/mg | View |
| 16 | PurerawzUnavailable | 30mg total | $101 | $3.36/mg | — | $3.39/mg | View |
| 17 | Felix Chemical Supply | 10mg total | $35 | $3.50/mg | — | $3.53/mg | View |
| 18 | Bluum Peptides | 10mg total | $39 | $3.90/mg | — | $3.93/mg | View |
| 19 | Modern Aminos | 10mg total | $42 | $4.20/mg | — | $4.23/mg | View |
| 20 | Ascend Bio LabsUnavailable | 30mg total3 Vials / 10MG each | $128 | $4.27/mg | 99.1% | $4.31/mg | View |
| 21 | Ez Peptides | 10mg total | $44 | $4.40/mg | 100.0% | $4.40/mg | View |
| 22 | Ascend Bio LabsUnavailable | 20mg total2 Vials / 10MG each | $90 | $4.50/mg | 99.1% | $4.54/mg | View |
| 23 | Ion PeptideUnavailable | 10mg total | $49 | $4.90/mg | — | $4.94/mg | View |
| 24 | Umbrella Labs | 10mg total10 Milligrams Peptide Vial each | $50 | $5.00/mg | — | $5.04/mg | View |
| 25 | Ascension PeptidesUnavailable | 10mg total | $50 | $5.00/mg | — | $5.04/mg | View |
| 26 | Ascend Bio LabsUnavailable | 10mg total | $53 | $5.30/mg | 99.1% | $5.35/mg | View |
| 27 | Simple PeptideUnavailable | 10mg total | $55 | $5.50/mg | — | $5.54/mg | View |
| 28 | Bluum Peptides | 5mg total | $29 | $5.80/mg | — | $5.84/mg | View |
| 29 | Chameleon PeptidesUnavailable | 100mg total10mg · 10-vial kit each | $581 | $5.81/mg | 99.2% | $5.86/mg | View |
| 30 | Chameleon Peptides | 50mg total5mg · 10-vial kit each | $308 | $6.16/mg | 99.2% | $6.21/mg | View |
| 31 | Chameleon Peptides | 50mg total10mg · 5-vial pack each | $323 | $6.46/mg | 99.2% | $6.51/mg | View |
| 32 | Chameleon Peptides | 10mg total | $68 | $6.84/mg | 99.2% | $6.89/mg | View |
| 33 | Behemoth LabzUnavailable | 10mg total | $69 | $6.85/mg | — | $6.90/mg | View |
| 34 | Behemoth Labz | 10mg total | $69 | $6.85/mg | — | $6.90/mg | View |
| 35 | PurerawzUnavailable | 10mg total | $69 | $6.88/mg | — | $6.93/mg | View |
| 36 | Chameleon Peptides | 25mg total5mg · 5-vial pack each | $187 | $7.48/mg | 99.2% | $7.54/mg | View |
| 37 | Sports Technology Labs | 10mg total | $80 | $8.00/mg | — | $8.06/mg | View |
| 38 | Cernum Biosciences | 10mg total | $84 | $8.40/mg | — | $8.46/mg | View |
| Listed, but not rankable — no published strength to price per mg | |||||||
| — | Eternal Peptides | 1 vial | $19 | no size published | — | — | View |
| — | Nootropic Source | 1 vial | $25 | no size published | — | — | View |
| — | PurerawzUnavailable | 1 vial | $35 | no size published | — | — | View |
| — | Chameleon Peptides | 1 vial | $40 | no size published | 99.2% | — | View |
| — | Cernum BiosciencesUnavailable | 1 vial | $44 | no size published | — | — | View |
| — | Ascend Bio LabsUnavailable | 1 Bottle | $65 | no size published | 99.1% | — | View |
| — | Ascend Bio LabsUnavailable | 2 Bottles | $128 | no size published | 99.1% | — | View |
Real $/active mg divides the price-per-mg by the measured purity — the honest cost of the actual peptide, so a 90%-pure vial isn’t compared as if it were 99%. Too cheap? flags a listing far below the market rate — often underdosing or a fake, not a deal. The crown marks the cheapest non-outlier; best value marks the lowest real cost per active mg. A vendor shown as Unavailable or Low stock is priced here but not currently buyable.
Independent testing
Semax — independent lab tests
Real, publicly verifiable third-party tests. Purity is read from the certificate itself. A test reflects one lab’s result for one submitted batch — not a guarantee that every vial matches.
How does this data get here?
Every record below is a real certificate of analysis, gathered two ways: from the public verification feeds that independent labs (like Janoshik) publish, and from the certificates vendors post on their own product pages. We open each certificate document and read the measured purity, content, batch, and date directly off it — a scraper can’t read a number printed inside an image, so this is done by machine vision, then recorded here with a link back to the original.
Nothing here is typed in by a vendor or invented by us. Where a certificate is missing, we say so rather than filling the gap.
We re-check the lab feed, too. A “still listed” tag means the certificate is currently public in Janoshik’s database — we re-verify against the live feed and stamp the date. If a cert is later pulled, the tag flips. It’s a freshness check on the same source, not a second independent opinion.
What a certificate does & doesn’t prove
Three different questions. Purity (“how clean?”), identity (“is it the right molecule?”, a mass-spec test), and content (“did I get the labeled mg?”) are separate. A vial can be 99% pure and still be the wrong peptide, or the right peptide underdosed. We flag the measured dose against the label above; underdosing is the most common real fraud.
Who submitted the sample matters. Most of these are vendor-submitted — the seller chose which vial to send, so one good certificate doesn’t prove every batch is the same. The gold standard is a blind test, where a buyer sends a vial they bought as a normal customer. Same label doesn’t prove same product; same batch number doesn’t prove same batch.
100.0%
highest tested purity
| Certificate | Manufacturer | Batch | Purity | Content / dose | Lab | |
|---|---|---|---|---|---|---|
| EZ Peptides | EZP-SEMX1003072026-09 | 99.96% | 11.28 mg; 11.46 mg; 11.48 mg | Janoshik Analytical | Verify | |
| cocerpeptides.com | CS-nasa10-0509 | 99.91% | 12.55/10mg · | Janoshik Analytical Still listed | Verify | |
| cocerpeptides.com | CS-nasa10-0408 | 99.56% | 13.08 mg | Janoshik Analytical Still listed | Verify | |
| https://www.htraresearch.cn | — | 99.28% | 5.68/5mg · full | Janoshik Analytical Still listed | Verify | |
 | Chameleon Peptides | — | 99.24% | 5.37 mg | Janoshik Analytical | View |
| Ascend Bio Labs | V260602-23-007 | 99.10% | — | Vanguard Laboratory | Verify | |
| https://crystalpeptides.eu/ | Se1010CP | 99.02% | 9.58 mg | Janoshik Analytical Still listed | Verify | |
| www.innopeptide.com | — | See report | — | Janoshik Analytical | Verify | |
| longevityprolabs.com | — | See report | — | Janoshik Analytical | Verify | |
 | Nootropic Source | — | 99.65% | — | Vendor self-tested | View |
Tested batches
Batch test records for Semax
The full test history for one batch — who picked the sample, who tested it, and what came back. It describes the vials that were tested, never every vial they sold.
What the research says
Scientific evidence & regulatory status
What the published literature actually shows about Semax — separate from any vendor’s marketing. Each finding links to its paper. This is education, not medical or dosing advice.
Regulatory status
No FDA-approved drug
Not FDA- or EMA-approved; registered and used clinically in Russia as a nootropic, a synthetic ACTH(4-10) analog. FDA placed semax (heptapeptide) in category 2 (significant safety risks) for compounding, citing immunogenicity risk by some routes and peptide-related impurities; the nomination was later withdrawn.
Honest overall read
Semax has decades of clinical use in Russia with supportive but low-quality human evidence (mostly small, open-label, Russian-language trials) plus animal/mechanistic BDNF/NGF data; there are no rigorous double-blind placebo-controlled Western trials, so its benefits remain unproven by contemporary standards.
An open-label study of 110 post-stroke patients found that adding semax to early rehabilitation raised plasma BDNF levels, sped functional recovery, and improved motor performance versus controls.
Open-label, unblinded, single-country (Russian) data; risk of bias is high and results have not been independently replicated in the West.
read the sourceCommonly researched together
Often stacked with Semax
Compounds the research community frequently discusses alongside Semax. Not a protocol or a recommendation — a starting point for what to read about next.
Research-use-only — not FDA-approved
Sold “for research use only,” this compound is not FDA-approved for human use and has not been evaluated for safety, purity, or sterility in people. It is generally not a scheduled controlled substance, so buying it as a research chemical is typically not itself a drug crime — but marketing or using it as a drug is not lawful, and it is not a dietary supplement.
General information, not legal or medical advice. VialGrade sells nothing and encourages no human use.
Research notes aren’t product proof
Research summaries describe published literature and market data only. They do not establish the identity, quality, safety, or legal status of any listed physical product.