VIP

A 28-amino-acid neuropeptide that binds VPAC1/VPAC2 receptors, triggering anti-inflammatory signaling, smooth muscle relaxation, vasodilation, and regulatory T-cell activity.

Mechanism of action from published research — how the molecule behaves, not a claim about any product or any human-use effect.

Studied for chronic inflammatory response syndrome (mold/biotoxin illness) and, as the synthetic analog aviptadil, for severe COVID-19 respiratory failure and other pulmonary conditions.

• Immune & thymicStudied in immune-modulation and thymic-function research.
• Recovery & healingStudied in tissue-repair research — tendon, ligament, muscle, and wound-healing models.

In clinical trials — aviptadil (synthetic VIP) received FDA Fast Track designation and reached Phase 2/3 trials for critical COVID-19; VIP protocols for CIRS rely on smaller, less rigorous trials.

Where the science stands — an approved drug is not the same as the research-grade material a vendor sells, which is unregulated regardless.

• Independent purity. Look for a third-party COA (Janoshik or MZ) showing a measured purity — not just a number the vendor typed.
• Batch match. The strongest evidence is a certificate for the exact batch you’ll receive, attributed to this vendor — check the cross-verification on the listing.
• Vendor reputation. See how the vendor is talked about in the community before trusting a new name.

Research context only — VialGrade never gives dosing, medical, or human-use guidance.