Live data — every record is aggregated from real public sources. VialGrade never sells; it links out to the vendor.
VialGrade
All compounds
Neuropeptide
Live data

VIP

Immune & thymicRecovery & healing

Vasoactive intestinal peptide, studied in immune and inflammatory research.

Vasoactive Intestinal PeptideAviptadil

Get told when a price moves or a lab test changes.

Observed median price

$60

Δ —
Every observation
DateObserved
$42.23
$79.06
$60.00
$60.00
$60.00
$60.00
$69.53
$69.53
$69.53
$69.53
$69.53
$60.00
$69.53
$69.53
$69.53
$69.53
$69.53
$69.53
$69.53
$69.53
$69.53
$69.53
$69.53
$69.53
$69.53
$69.53
$60.00
$60.00
$60.00
$60.00
$60.00
$60.00
$60.00
$60.00
$68.10
$68.10
$60.00

Not enough listings with 30 days of checks to summarise a change — 1 of 7 qualify so far.

7

Active listings

0

Independent lab tests

$42–$95

Observed price range

3

Known aliases

Understand this compound

What is VIP?

In clinical trialsa.k.a. Aviptadil (synthetic analog)

A messenger molecule your body uses to relax airways, widen blood vessels, and calm inflammation. Studied for mold-related illness and, as a synthetic version, for severe respiratory failure.

Immune & thymicRecovery & healing
⚠

Good to know: Its use for mold-related illness comes from a specific clinical framework with a limited evidence base, distinct from the more rigorously trialed aviptadil respiratory research.

How does VIP work?

The science

A 28-amino-acid neuropeptide that binds VPAC1/VPAC2 receptors, triggering anti-inflammatory signaling, smooth muscle relaxation, vasodilation, and regulatory T-cell activity.

Mechanism of action from published research — how the molecule behaves, not a claim about any product or any human-use effect.

What is VIP researched for?

Studied for chronic inflammatory response syndrome (mold/biotoxin illness) and, as the synthetic analog aviptadil, for severe COVID-19 respiratory failure and other pulmonary conditions.

  • Immune & thymicStudied in immune-modulation and thymic-function research.
  • Recovery & healingStudied in tissue-repair research — tendon, ligament, muscle, and wound-healing models.
How far has the research gone?

In clinical trials — aviptadil (synthetic VIP) received FDA Fast Track designation and reached Phase 2/3 trials for critical COVID-19; VIP protocols for CIRS rely on smaller, less rigorous trials.

Where the science stands — an approved drug is not the same as the research-grade material a vendor sells, which is unregulated regardless.

What should I check before buying?
  • Independent purity. Look for a third-party COA (Janoshik or MZ) showing a measured purity — not just a number the vendor typed.
  • Batch match. The strongest evidence is a certificate for the exact batch you’ll receive, attributed to this vendor — check the cross-verification on the listing.
  • Vendor reputation. See how the vendor is talked about in the community before trusting a new name.

Research context only — VialGrade never gives dosing, medical, or human-use guidance.

Current market

The VIP market

Every VIP listing we track — 7 in all. The standout picks first where the evidence supports them, then the full table, ranked by what a milligram really costs wherever the vendor published a strength we can read.

Open full market

Compare by real cost

Every VIP listing, cheapest per mg first

Sticker prices hide the size, so listings are ranked by what a milligram actually costs — with independently tested purity where it exists. All 7 are here: the last 3 are listings whose vendor never published a strength we can read, so they have no per-mg figure to sort on.

#VendorSizePricePer mgTested purityReal $/active mg
1Behemoth LabzUnavailable10mg total$77$7.74/mg——View
2Behemoth LabzUnavailable12mg total$94$7.85/mg——View
3Purerawz10mg total$79$7.91/mg——View
4Purerawz12mg total$95$7.95/mg——View
Listed, but not rankable — no published strength to price per mg
—Behemoth Labz1 vial$42no size published——View
—Purerawz1 vial$42no size published——View
—Modern Aminos1 vial$60no size published——View

Open the full VIP market

Real $/active mg divides the price-per-mg by the measured purity — the honest cost of the actual peptide, so a 90%-pure vial isn’t compared as if it were 99%. Too cheap? flags a listing far below the market rate — often underdosing or a fake, not a deal. The crown marks the cheapest non-outlier; best value marks the lowest real cost per active mg. A vendor shown as Unavailable or Low stock is priced here but not currently buyable.

What the research says

Scientific evidence & regulatory status

What the published literature actually shows about VIP — separate from any vendor’s marketing. Each finding links to its paper. This is education, not medical or dosing advice.

Regulatory status

No FDA-approved drug

Not FDA-approved: two US emergency-use requests for aviptadil in COVID-19 respiratory failure were declined, and FDA lists vasoactive intestinal peptide in category 1 of the section 503A compounding nominations, meaning it is under evaluation rather than approved. A combination of aviptadil with phentolamine (Invicorp) is authorized in the UK for erectile dysfunction.

US legal status

Research-use-only — not FDA-approved

Sold “for research use only,” this compound is not FDA-approved for human use and has not been evaluated for safety, purity, or sterility in people. It is generally not a scheduled controlled substance, so buying it as a research chemical is typically not itself a drug crime — but marketing or using it as a drug is not lawful, and it is not a dietary supplement.

Read the full US law →

General information, not legal or medical advice. VialGrade sells nothing and encourages no human use.

Research notes aren’t product proof

Research summaries describe published literature and market data only. They do not establish the identity, quality, safety, or legal status of any listed physical product.