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Synthetic peptide
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KPV

Gut healthRecovery & healingImmune & thymic

A tripeptide (lysine-proline-valine) corresponding to the C-terminal fragment of alpha-melanocyte-stimulating hormone.

Lys-Pro-ValLysine-Proline-Valine

Observed median price

$57

0%

3

Active listings

0

Independent lab tests

$37–$140

Observed price range

3

Known aliases

Understand this compound

What is KPV?

Preclinical / animal onlya.k.a. Lysine-Proline-Valine

A short anti-inflammatory tripeptide studied in gut and inflammatory-condition research, often paired with BPC-157 for gut-focused stacks.

Gut healthRecovery & healingImmune & thymic

Good to know: No human clinical trials have been conducted; anti-inflammatory claims rest entirely on cell-culture and rodent colitis models.

How does KPV work?

A tripeptide (Lys-Pro-Val) representing the C-terminal fragment of alpha-MSH that suppresses NF-κB nuclear translocation and downstream pro-inflammatory cytokine production, independent of melanocortin receptor activation.

Mechanism of action from published research — how the molecule behaves, not a claim about any product or any human-use effect.

What is KPV researched for?

Studied mainly for gut, skin, and lung inflammation, including inflammatory bowel disease models.

  • Gut healthStudied in gastrointestinal research, including gut-lining integrity and inflammatory-condition models.
  • Recovery & healingStudied in tissue-repair research — tendon, ligament, muscle, and wound-healing models.
  • Immune & thymicStudied in immune-modulation and thymic-function research.
How far has the research gone?

Preclinical / animal research — roughly two dozen studies since 2001, all in cell culture or animal models, with no completed human trials.

Where the science stands — an approved drug is not the same as the research-grade material a vendor sells, which is unregulated regardless.

What should I check before buying?
  • Independent purity. Look for a third-party COA (Janoshik or MZ) showing a measured purity — not just a number the vendor typed.
  • Batch match. The strongest evidence is a certificate for the exact batch you’ll receive, attributed to this vendor — check the cross-verification on the listing.
  • Vendor reputation. See how the vendor is talked about in the community before trusting a new name.

Research context only — VialGrade never gives dosing, medical, or human-use guidance.

US legal status

Research-use-only — not FDA-approved

Sold “for research use only,” this compound is not FDA-approved for human use and has not been evaluated for safety, purity, or sterility in people. It is generally not a scheduled controlled substance, so buying it as a research chemical is typically not itself a drug crime — but marketing or using it as a drug is not lawful, and it is not a dietary supplement.

Read the full US legal overview →

General information, not legal or medical advice. VialGrade sells nothing and encourages no human use.

Current market

All KPV listings

Commonly researched together

Often stacked with KPV

Compounds the research community frequently discusses alongside KPV. Not a protocol or a recommendation — a starting point for what to read about next.

Research notes aren’t product proof

Research summaries describe published literature and market data only. They do not establish the identity, quality, safety, or legal status of any listed physical product.