TB-500
A fragment of thymosin beta-4 studied in recovery, flexibility, and tissue-repair research. Almost always discussed alongside BPC-157.
Get told when a price moves or a lab test changes.
Observed median price
$70
Every observation
| Date | Observed |
|---|---|
| $58.00 | |
| $59.00 | |
| $71.45 | |
| $71.45 | |
| $71.45 | |
| $71.45 | |
| $71.45 | |
| $71.45 | |
| $70.00 | |
| $71.45 | |
| $71.45 | |
| $71.45 | |
| $71.45 | |
| $70.00 | |
| $70.00 | |
| $70.00 | |
| $70.00 | |
| $70.00 | |
| $71.45 | |
| $70.00 | |
| $70.00 | |
| $70.00 | |
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| $70.00 | |
| $70.00 | |
| $70.00 | |
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| $70.00 | |
| $60.50 | |
| $60.50 | |
| $69.99 | |
| $69.99 |
Median of 8 listings' 30-day changes; 11 excluded for insufficient history.
19
Active listings
6 · 99.5%
Independent lab tests
$26–$567
Observed price range
4
Known aliases
Read from the certificate, not re-measured by VialGrade. Purity is not a grade. Purity vs grade
Understand this compound
What is TB-500?
Preclinical / animal onlya.k.a. TB4 Fragment (marketing name)A lab-made piece of a repair protein found in nearly every cell of your body, which helps cells move to where damage is. The classic partner to BPC-157 in recovery research — though the injectable version itself has never been tested in people.
Good to know: TB-500 is frequently conflated with thymosin beta-4, which has real human data as an eye-drop formulation — that data does not establish safety or efficacy for injectable TB-500.
How does TB-500 work?
The science
Marketed as a synthetic fragment of thymosin beta-4, intended to mimic that protein's actin-binding, cell-migration-promoting activity in wound and tendon repair.
Mechanism of action from published research — how the molecule behaves, not a claim about any product or any human-use effect.
What is TB-500 researched for?
Studied (as the parent molecule thymosin beta-4, not as TB-500 itself) for wound healing, cardiac tissue repair, and corneal healing.
- Recovery & healingStudied in tissue-repair research — tendon, ligament, muscle, and wound-healing models.
- Muscle & performanceStudied in muscle-growth, repair, and physical-performance research.
How far has the research gone?
Preclinical / animal research — favorable data come almost entirely from animal studies of full-length thymosin beta-4; injectable TB-500 itself has not been tested in human trials.
Where the science stands — an approved drug is not the same as the research-grade material a vendor sells, which is unregulated regardless.
What should I check before buying?
- Independent purity. Look for a third-party COA (Janoshik or MZ) showing a measured purity — not just a number the vendor typed.
- Batch match. The strongest evidence is a certificate for the exact batch you’ll receive, attributed to this vendor — check the cross-verification on the listing.
- Vendor reputation. See how the vendor is talked about in the community before trusting a new name.
Research context only — VialGrade never gives dosing, medical, or human-use guidance.
Current market
The TB-500 market
Every TB-500 listing we track — 19 in all. The standout picks first where the evidence supports them, then the full table, ranked by what a milligram really costs wherever the vendor published a strength we can read.
Open full marketTB-500 Frag 17-23 10mg 10mg
EZ PeptidesA
$48$4.80/mg-38% vs median
Lowest price per mg that isn't flagged as suspiciously cheap.
In stockChecked 7 hours ago
TB-500 (5MG)
Ascension Peptides
$54$10.8/mg+39% vs median
The most recently re-verified listing on this market.
UnavailableChecked 6 hours ago
Drops – TB-500 | 30mg
Ion PeptideC
$149$4.97/mg-36% vs median
Ranked #2 of 14 listings by price per milligram.
UnavailableChecked 17 days ago
TB-500 10mg · 10-vial kit
Chameleon PeptidesA
$567$5.67/mg-27% vs median
Ranked #3 of 14 listings by price per milligram.
In stockChecked 4 days ago
TB-500 10mg · 5-vial pack
Chameleon PeptidesA
$344$6.88/mg-11% vs median
Ranked #4 of 14 listings by price per milligram.
In stockChecked 4 days ago
Compare by real cost
Every TB-500 listing, cheapest per mg first
Sticker prices hide the size, so listings are ranked by what a milligram actually costs — with independently tested purity where it exists. All 19 are here: the last 5 are listings whose vendor never published a strength we can read, so they have no per-mg figure to sort on.
| # | Vendor | Size | Price | Per mg | Tested purity | Real $/active mg | |
|---|---|---|---|---|---|---|---|
| 1 | Ez Peptides | 10mg total | $48 | $4.80/mg | 99.9% | $4.81/mgbest value | View |
| 2 | Ion PeptideUnavailable | 30mg total | $149 | $4.97/mg | — | $4.99/mg | View |
| 3 | Chameleon Peptides | 100mg total10mg · 10-vial kit each | $567 | $5.67/mg | — | $5.70/mg | View |
| 4 | Chameleon Peptides | 50mg total10mg · 5-vial pack each | $344 | $6.88/mg | — | $6.92/mg | View |
| 5 | Bluum Peptides | 10mg total | $69 | $6.90/mg | — | $6.93/mg | View |
| 6 | Felix Chemical Supply | 10mg total | $70 | $7.00/mg | — | $7.03/mg | View |
| 7 | Swiss Chems | 30mg total0.5mg each | $255 | $8.50/mg | — | $8.54/mg | View |
| 8 | Swiss Chems | 10mg total | $97 | $9.70/mg | — | $9.74/mg | View |
| 9 | Bluum Peptides | 5mg total | $49 | $9.80/mg | — | $9.85/mg | View |
| 10 | Behemoth LabzUnavailable | 5mg total | $52 | $10.5/mg | — | $10.5/mg | View |
| 11 | Behemoth LabzUnavailable | 10mg total | $105 | $10.5/mg | — | $10.5/mg | View |
| 12 | Ascension PeptidesUnavailable | 5mg total | $54 | $10.8/mg | — | $10.8/mg | View |
| 13 | Cernum Biosciences | 10mg total | $130 | $13.0/mg | — | $13.1/mg | View |
| 14 | Sports Technology Labs | 5mg total | $70 | $14.0/mg | — | $14.1/mg | View |
| Listed, but not rankable — no published strength to price per mg | |||||||
| — | Eternal Peptides | 1 vial | $26 | no size published | — | — | View |
| — | Nootropic Source | 1 vial | $40 | no size published | — | — | View |
| — | Swiss Chems | 1 vial | $49 | no size published | — | — | View |
| — | Chameleon Peptides | 1 vial | $73 | no size published | — | — | View |
| — | Cernum Biosciences | 1 vial | $80 | no size published | — | — | View |
Real $/active mg divides the price-per-mg by the measured purity — the honest cost of the actual peptide, so a 90%-pure vial isn’t compared as if it were 99%. Too cheap? flags a listing far below the market rate — often underdosing or a fake, not a deal. The crown marks the cheapest non-outlier; best value marks the lowest real cost per active mg. A vendor shown as Unavailable or Low stock is priced here but not currently buyable.
Independent testing
TB-500 — independent lab tests
Real, publicly verifiable third-party tests. Purity is read from the certificate itself. A test reflects one lab’s result for one submitted batch — not a guarantee that every vial matches.
How does this data get here?
Every record below is a real certificate of analysis, gathered two ways: from the public verification feeds that independent labs (like Janoshik) publish, and from the certificates vendors post on their own product pages. We open each certificate document and read the measured purity, content, batch, and date directly off it — a scraper can’t read a number printed inside an image, so this is done by machine vision, then recorded here with a link back to the original.
Nothing here is typed in by a vendor or invented by us. Where a certificate is missing, we say so rather than filling the gap.
We re-check the lab feed, too. A “still listed” tag means the certificate is currently public in Janoshik’s database — we re-verify against the live feed and stamp the date. If a cert is later pulled, the tag flips. It’s a freshness check on the same source, not a second independent opinion.
What a certificate does & doesn’t prove
Three different questions. Purity (“how clean?”), identity (“is it the right molecule?”, a mass-spec test), and content (“did I get the labeled mg?”) are separate. A vial can be 99% pure and still be the wrong peptide, or the right peptide underdosed. We flag the measured dose against the label above; underdosing is the most common real fraud.
Who submitted the sample matters. Most of these are vendor-submitted — the seller chose which vial to send, so one good certificate doesn’t prove every batch is the same. The gold standard is a blind test, where a buyer sends a vial they bought as a normal customer. Same label doesn’t prove same product; same batch number doesn’t prove same batch.
99.9%
highest tested purity
| Certificate | Manufacturer | Batch | Purity | Content / dose | Lab | |
|---|---|---|---|---|---|---|
| https://crystalpeptides.eu/Blend | TB1045Cp | 99.93% | 10.17 mg | Janoshik Analytical Still listed | Verify | |
| EZ Peptides | EZP-TBF1006172026-06 | 99.88% | 11.38 mg; 11.41 mg; 11.36 mg | Janoshik Analytical | Verify | |
| PeptideGurusBlend | — | 99.75% | 41.95/40mg · full | Janoshik Analytical Still listed | Verify | |
| cocerpeptides.com | CS-tb10-0111 | 99.33% | 11.61/10mg · full | Janoshik Analytical Still listed | Verify | |
| www.certapeptides.comBlend | CP-2605-TB55 | 99.17% | 5.51/5mg · full | Janoshik Analytical Still listed | Verify | |
| Alpha BioPharmaBlend | BAZPEMCK | 98.71% | 10.65 mg | Janoshik Analytical Still listed | Verify | |
| Eternal Peptides | EP-260521-TB10 | 99.60% | — | Unverified lab · Kovera Labs | Verify | |
 | Chameleon Peptides | CP-8408241-P | 99.34% | 10.15 mg | Unverified lab · Horizon Analytical | View |
Tested batches
Batch test records for TB-500
The full test history for one batch — who picked the sample, who tested it, and what came back. It describes the vials that were tested, never every vial they sold.
What the research says
Scientific evidence & regulatory status
What the published literature actually shows about TB-500 — separate from any vendor’s marketing. Each finding links to its paper. This is education, not medical or dosing advice.
Regulatory status
No FDA-approved drug
Not FDA-approved; sold for research use only; WADA-prohibited (the full thymosin beta-4 protein is investigational as ophthalmic drug RGN-259)
Honest overall read
The full thymosin beta-4 peptide has legitimate human ophthalmic trial data (dry eye, corneal healing), but the injectable 'TB-500' fragment sold for muscle/tendon/injury recovery is a different product with only animal-level evidence.
In a Phase 2 randomized, double-masked, placebo-controlled trial (9 patients), thymosin beta-4 eye drops (RGN-259) produced statistically significant improvements in signs and symptoms of severe dry eye versus vehicle.
Very small sample; this tests the full thymosin beta-4 protein as an eye drop, not the injectable 'TB-500' fragment marketed to consumers.
read the sourceIn a randomized, placebo-controlled, double-masked Phase III trial, 0.1% RGN-259 (thymosin beta-4) ophthalmic solution promoted corneal healing in neurotrophic keratopathy, with complete healing in 6 of 10 treated versus 1 of 8 placebo subjects.
Applies only to the eye-drop formulation of full-length thymosin beta-4; systemic or injectable use for muscle/tendon healing has no human trials.
read the sourceCommonly researched together
Often stacked with TB-500
Compounds the research community frequently discusses alongside TB-500. Not a protocol or a recommendation — a starting point for what to read about next.
BPC-157
Synthetic peptide
One of the most-discussed peptides in tissue-recovery and gut-health research. Preclinical studies have looked at connective-tissue and gastrointestinal models. The classic partner to TB-500.
GHK-Cu
Copper peptide
A copper peptide famous in skincare and hair research for collagen and cosmetic contexts, also discussed for tissue recovery. The 'GLOW' in the popular recovery blend.
Research-use-only — not FDA-approved
Sold “for research use only,” this compound is not FDA-approved for human use and has not been evaluated for safety, purity, or sterility in people. It is generally not a scheduled controlled substance, so buying it as a research chemical is typically not itself a drug crime — but marketing or using it as a drug is not lawful, and it is not a dietary supplement.
General information, not legal or medical advice. VialGrade sells nothing and encourages no human use.
Research notes aren’t product proof
Research summaries describe published literature and market data only. They do not establish the identity, quality, safety, or legal status of any listed physical product.